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Cell permeable succinate bypasses statin−induced complex I mitochondrial dysfunction. Scheme 10. ubiquinone; e−, electron; FADH2, dihydroflavine-adenine dinucleotide; Fe+3, iron(III); Fe+2, iron(II); H+, proton; NAD+, Nicotinamide adenine dinucleotide oxidized form; NADH, Nicotinamide adenine dinucleotide reduced form; OXPHOS, oxidative phosphorylation.
