Table 2.
Summary of functional enrichment analysis results by Gene Ontology functions (BP: Biological Process, MF: Molecular Functions, CC: Cellular Component), and KEGG pathways. “Up” terms are overrepresented in female lung adenocarcinoma patients, while “Down” terms are overrepresented in male lung adenocarcinoma patients.
| Study | Significant GO BP Terms | Significant GO MF Terms | Significant GO CC Terms | Significant KEGG Pathways | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Up | Down | Total | Up | Down | Total | Up | Down | Total | Up | Down | Total | |
| GSE10072 | 26 | 153 | 179 | 29 | 8 | 37 | 16 | 40 | 56 | 1 | 5 | 6 |
| GSE19188 | 7 | 12 | 19 | 0 | 3 | 3 | 11 | 20 | 31 | 1 | 4 | 5 |
| GSE31210 | 21 | 2 | 23 | 0 | 0 | 0 | 4 | 0 | 4 | 8 | 2 | 10 |
| GSE32863 | 428 | 51 | 479 | 28 | 5 | 33 | 40 | 41 | 81 | 27 | 6 | 33 |
| GSE63459 | 0 | 26 | 26 | 0 | 3 | 3 | 8 | 27 | 35 | 1 | 4 | 5 |
| GSE75037 | 245 | 35 | 280 | 14 | 4 | 18 | 14 | 21 | 35 | 22 | 5 | 27 |
| GSE81089 | 2 | 1 | 3 | 7 | 1 | 8 | 7 | 4 | 11 | 1 | 1 | 2 |
| GSE87340 | 178 | 62 | 240 | 3 | 0 | 3 | 48 | 13 | 61 | 26 | 1 | 27 |
| TCGA | 294 | 228 | 522 | 28 | 30 | 58 | 21 | 70 | 91 | 30 | 17 | 47 |