Table 2.
Comparison between GEFC and REFC intensity values in eyes with and without diabetic macular edema.
| Macular Sector (ETDRS Grid) |
DME (no = 0/yes = 1) | GEFC Intensity | p Value * | REFC Intensity | p Value * |
|---|---|---|---|---|---|
| Fovea | 0 1 |
17.4 ± 14.1 43.3 ± 21.2 |
<0.001 ** | 18.5 ± 12.6 47.1 ± 21.4 |
<0.001 ** |
| Nasal 1.5 mm | 0 1 |
52.2 ± 25.9 54.7 ± 21.2 |
0.66 | 62 ± 23.3 62.7 ± 21.1 |
0.90 |
| Nasal 3 mm | 0 1 |
74.9 ± 23.5 68.5 ± 15.4 |
0.35 | 96.4 ± 25.3 88.6 ± 17.3 |
0.30 |
| Superior 1.5 mm | 0 1 |
53.2 ± 19.3 52 ± 21.6 |
0.38 | 64.2 ± 19.7 61 ± 21.7 |
0.44 |
| Superior 3 mm | 0 1 |
87.9 ± 21.9 75.2 ± 25.3 |
0.03 ** | 111.7 ± 26.7 89.2 ± 23.7 |
0.001 ** |
| Inferior 1.5 mm | 0 1 |
55.2 ± 18.4 53.7 ± 15.2 |
0.66 | 73.5 ± 79.8 62.5 ± 16.5 |
0.42 |
| Inferior 3 mm | 0 1 |
78.5 ± 20.6 74.7 ± 20.7 |
0.43 | 104.4 ± 88.9 93.2 ± 6.1 |
0.58 |
| Temporal 1.5 mm | 0 1 |
55.9 ± 19.7 50.7 ± 19.4 |
0.11 | 65.9 ± 19.8 60.3 ± 19.4 |
0.10 |
| Temporal 3 mm | 0 1 |
78.4 ± 21.8 64.9 ± 23.6 |
0.004 ** | 95 ± 23.1 79.4 ± 26.3 |
0.002 ** |
* Two-sided unpaired t-test: comparison between patients with and without DME in nine different sectors of a standard 6-mm ETDRS grid. Statistical significance was set at p = 0.05. ** Comparisons that reached statistical significance. Values are reported as mean ± SD. DME: diabetic macular edema; GEFC: green emission fluorescence component; REFC: red emission fluorescence component; SD: standard deviation; ETDRS: early treatment diabetic retinopathy study.