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AGEs pathway. Fructose, which is an end-product of the polyol pathway, is converted to 3-deoxyglucosone and glyceraldehyde 3-phosphate is converted to methylglyoxal. 3-deoxyglucosone and methylglyoxal are intermediate products of AGEs. AGEs, advanced glycation end-products: Glut, glucose transporter; TCA cycle, tricarboxylic acid cycle.
