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Pentose phosphate pathway. Glucose 6-phosphate is metabolized to a series of pentoses, such as ribose 5-phosphate. Transketolase catalyzes the conversion of ribose 5-phosphate into fructose 6-phosphate and glyceraldehyde 3-phosphate. DPN, diabetic polyneuropathy; Glut, glucose transporter; GSH, glutathione; NADP(H), nicotinamide adenine dinucleotide phosphate; TCA cycle, tricarboxylic acid cycle.
