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. 2021 Jan 5;26(1):230. doi: 10.3390/molecules26010230

Table 2.

IC50 values obtained for alkaloid standards and plant extracts (concentration of acetylcholinesterase 0.2 U/mL).

Alkaloid Concentration of Acetylcholinesterase 0.2 U/mL
IC50 (µg/mL) IC50 (µM)
Berberine 0.36 (±0.03) 1.06
Chelerythrie 0.25 (±0.02) 0.72
Chelidonine 9.53 (±0.43) 26.97
Protopine 23.13 (±0.91) 69.81
Sanguinarie 1.85 (±0.12) 5.57
Sanguinaria canadensis Extracts
Before flowering 89.14 (±4.03) -
During flowering 61.24 (±3.12) -
After flowering 64.12 (±3.34) -

-: the value cannot be calculated for extract.