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. 2020 Dec 28;22(1):199. doi: 10.3390/ijms22010199

Table 4.

Human studies using synbiotics.

Conditions Treatment Main Results Ref
Human HE Mixture of 4 probiotics (L. paracasei + L. plantarum + Leuconostoc mesenteriodes + P. pentosaceus) with 4 fibers (oat bran, pectin, resistant starch, and inulin) No change in cognitive function [103]
Cirrhosis with MHE Mixture of 4 probiotics (P. pentoseceus + Leuconostoc mesenteroides + L. paraacasei + L. plantarum) with 3 fibers (beta glucan + pectin + resistant starch) (↓): TBIL
(↑): ALB
[104]

↑ indicates an increase in condition, ↓ indicates a decrease in condition, ALB, albumin; HE, hepatic encephalopathy; MHE, minimal hepatic encephalopathy; TBIL, total bilirubin