Anticarcinogenic effects |
Catechins |
support therapy as well as in cancer prevention, inhibiting tumour growth factors and inducing apoptosis of cancer cells |
[58], [61] |
Vitamin C |
protective effects against cancer |
[62] |
Phenolic acids |
inhibiting cancer cell growth and prevent metastasis |
[34] |
EGCG |
inhibiting tumour angiogenesis, antioxidant effects and suppressing the inflammatory processes contributing to transformation, hyperproliferation and initiation of carcinogenesis, improving tissue sensitivity to insulin and leptin, and reducing blood lipid parameters; |
[57], [58], [59], [61] |
Anti-inflammatory effects |
EGCG |
scavenging ROS, regulating the inflammatory condition and response |
[22], [66] |
Cardioprotective
|
EGCG |
reducing oxidative stress, inhibiting the activation of stress-activated protein kinase and signalling pathways inducing the inflammatory response |
[69], [70] |
Rutin |
strengthening blood vessels |
[36] |
Improvement of cognitive function and prevention of neurodegenerative disorders
|
EGCG |
promote clarity of mind and cognitive function, inhibits LPS-induced production of reactive oxygen species, improves insulin sensitivity and decreases amyloid-β production in the brain |
[92], [98], [99] |
Caffeine |
reduce the risk of cognitive decline, reversing oxidative processes and reducing neuroinflammation, inhibit ageing of the brain, anti-inflammatory effects, decreased deposition of amyloid-β in the brain |
[94], [95], [96], [97] |
Regulation of carbohydrate metabolism |
EGCG |
inhibiting starch digestion, inhibiting gluconeogenesis and the absorption of lipids and glucose, improving insulin sensitivity |
[89], [91] |
Quercetin |
inhibiting glucose absorption, regulating insulin secretion, improving insulin sensitivity |
[43] |
Phenolic acids |
modulating lipid and carbohydrate metabolism |
[35] |