Figure 1.

(a) Chemical structures of Nevirapine (NVP), Oxcarbazepine (OXC) and the soluble analogue of the chiral selector (R,R) Whelk-O1. (b) (pR) and (pS) conformational enantiomers of NVP and OXC. (b) With reference to the molecules of NVP and OXC, in the figure, the atom outside of but closest to the chiral plane (the “pilot atom”) has been assigned the letter P. Starting from P, the three atoms closest to it and lying on the plane, chosen according to CIP rules, have been assigned the letters a, b and c. When the succession of the a, b and c atoms in the chiral plane forms a clockwise array, the assigned configuration is pR, while if the array is counterclockwise, the assigned configuration is pS.