Figure 5.
Abnormal chromosome plate in arrested zygote stage embryos treated with STAT3 inhibitor S3I-201. (A) Representative images of abnormal metaphase chromosome plates in arrested zygotes after treatment with 100-μM S3I-201 inhibitor in KSOM-AA embryo culture medium. Chromosomal DNA was stained with DAPI, a blue fluorescent dye. All samples were analyzed under a laser scanning confocal microscope. Scale bar = 20 µm. (B) Representative images of the different morphologies of the abnormal metaphase chromosome plates.