Table 5.

Multivariate Cox hazard model predicting MACCE and cardiac death

Variable	MACCE		Cardiac death
	HR (95%CI)	p	HR (95%CI)	p
Age ≥ 65 years	0.83 (0.53–1.301)	0.42	0.41 (0.143–1.164)	0.09
Sexa	1.4 (0.838–2.334)	0.2	2.1 (0.709–6.216)	0.18
HT	0.92 (0.571–1.464)	0.71	1.21 (0.403–3.628)	0.73
DM	0.81 (0.526–1.233)	0.32	0.71 (0.271–1.857)	0.49
HP	0.91 (0.604–1.377)	0.66	0.97 (0.376–2.479)	0.94
EF < 0.5	2.11 (1.326–3.365)	0.002	5.12 (2.053–12.742)	< 0.001
eGFR < 60 ml/min	2.06 (1.223–3.484)	0.007	5.33 (1.998–14.237)	0.001
LM disease	1.16 (0.703–1.913)	0.56	3.69 (1.466–9.296)	0.006
CTO recanalization	0.56 (0.365–0.863)	0.009	0.28 (0.091–0.88)	0.03

^aFor women vs. men; multivariable Cox hazards regression analysis performed in the overall CTO patients