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. 2021 Jan 9;21:39. doi: 10.1186/s12884-020-03486-7

Table 2.

Pregnancy outcomes among different infertility etiologies for IVF compared to spontaneous pregnancies in singleton pregnancies

Control Ovulation disorder Tubal disease Endometriosis Male infertility Mixed infertility
Singleton pregnancies N % N % N % N % N % N %
Maternal outcomes 6832 271 542 74 267 87
Gestational hypertension 271 4 13 4.8 18 3.3 3 4.1 18 6.7^ 2 2.3
Preeclampsia 193 2.8 22 8.1* 23 4.2 2 2.7 9 3.4 4 4.6
 Mild 63 0.9 8 3* 7 1.3 0 0 2 0.2 1 1.1
 Severe 130 1.9 14 5.2* 16 3 2 2.7 7 2.6 3 3.4
Preterm preeclampsia 46 0.7 8 3* 5 0.9 0 0 3 1.1 2 2.3
GDM 1132 16.6 76 28* 129 23.8* 15 20.3 57 21.3^ 25 28.7^
Placenta previa 94 1.4 3 1.1 18 3.3^ 8 10.8^ 13 4.9* 5 5.7*
Placental abruption 92 1.3 7 2.6 7 1.3 2 2.7 2 0.7 4 4.6^
pPROM 154 2.3 13 4.8^ 19 3.5 3 4.1 11 4.1 3 3.4
Placenta accreta 148 2.2 7 2.6 20 3.7^ 3 4.1 11 4.1^ 3 3.4
Postpartum haemorrhage 574 8.4 31 11.4 59 10.9^ 6 8.1 21 7.9 9 10.3
ICP 16 0.2 3 1.1^ 4 0.7^ 0 0 1 0.4 0 0
Polyhydramnios 61 0.9 4 1.5 7 1.3 1 1.4 5 1.9 0 0
Oligohydramnios 247 3.6 14 5.2 18 3.3 4 5.4 12 4.5 2 2.3
Chorioamnionitis 91 1.4 7 2.6 10 1.8 2 2.7 3 1.1 4 4.6^

Note: GDM Gestational diabetes mellitus, pPROM preterm premature rupture of membranes, ICP intrahepatic cholestasis of pregnancy; Mixed infertility refers to multiple infertility-related diagnosis. Data are presented as n (%) for dichotomous variable, P values were assessed by using the Pearson’s chi-square test, or Fisher’s exact test between each infertility subgroup vs controls ; P ≤ 0.001 = *; P < 0.05 = ^. Nonsignificant numbers have not symbol