Table 4.
cORs, aORs and 95% CIs of pregnancy and delivery outcomes among different infertility etiologies compared to spontaneous pregnancies in singleton pregnancies
| Ovulation disorder | Tubal disease | Endometriosis | Male infertility | Mixed infertility | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP | cOR | aOR | 95% CI | cOR | aOR | 95% CI | cOR | aOR | 95% CI | cOR | aOR | 95% CI | cOR | aOR | 95% CI | |||||
| GH | 0.63 | 0.93 | 0.52 | 1.68 | 0.91 | 0.72 | 0.44 | 1.19 | 1.06 | 0.90 | 0.28 | 2.89 | 0.55 | 1.49 | 0.90 | 2.47 | 1.76 | 0.45 | 0.11 | 1.85 |
| Preeclampsia | 0.26 | 2.60 | 1.61 | 4.20 | 0.44 | 1.40 | 0.89 | 2.21 | 0.75 | 0.90 | 0.22 | 3.74 | 0.44 | 1.10 | 0.55 | 2.20 | 0.60 | 1.39 | 0.50 | 3.90 |
| Mild | 0.30 | 2.67 | 1.23 | 5.79 | 0.57 | 1.20 | 0.54 | 2.68 | 0.99 | NC | NC | NC | 0.93 | 0.67 | 0.16 | 2.77 | 0.80 | 0.98 | 0.13 | 7.19 |
| Severe | 0.25 | 2.46 | 1.36 | 4.44 | 0.40 | 1.51 | 0.88 | 2.59 | 0.67 | 1.42 | 0.34 | 5.92 | 0.35 | 1.36 | 0.62 | 2.99 | 0.54 | 1.62 | 0.49 | 5.29 |
| PPE | 0.10 | 4.52 | 2.03 | 10.06 | 0.22 | 1.38 | 0.54 | 3.54 | 0.72 | NC | NC | NC | 0.18 | 1.66 | 0.50 | 5.49 | 0.29 | 3.37 | 0.79 | 14.46 |
| GDM | 0.43 | 1.76 | 1.33 | 2.33 | 0.72 | 1.50 | 1.21 | 1.86 | 0.73 | 1.20 | 0.67 | 2.13 | 0.72 | 1.31 | 0.96 | 1.77 | 0.49 | 1.85 | 1.15 | 2.98 |
| Placenta previa | 1.40 | 0.93 | 0.29 | 3.00 | 0.47 | 2.70 | 1.59 | 4.59 | 0.14 | 9.33 | 4.22 | 20.62 | 0.39 | 4.14 | 2.23 | 7.68 | 0.23 | 4.73 | 1.83 | 12.21 |
| Placental abruption | 0.68 | 1.89 | 0.86 | 4.17 | 1.36 | 0.92 | 0.42 | 2.01 | 0.72 | 1.90 | 0.46 | 7.97 | 1.82 | 0.55 | 0.13 | 2.25 | 0.28 | 3.39 | 1.20 | 9.56 |
| pPROM | 0.23 | 2.11 | 1.17 | 3.81 | 0.36 | 1.52 | 0.93 | 2.49 | 0.47 | 1.76 | 0.55 | 5.70 | 0.27 | 1.79 | 0.95 | 3.37 | 0.65 | 1.49 | 0.46 | 4.80 |
| Placenta accreta | NC | 1.29 | 0.59 | 2.80 | NC | 1.78 | 1.10 | 2.89 | NC | 2.00 | 0.62 | 6.48 | NC | 2.05 | 1.08 | 3.87 | NC | 1.70 | 0.53 | 5.48 |
| PH | 0.65 | 1.57 | 1.04 | 2.36 | 0.65 | 1.61 | 1.19 | 2.18 | 0.66 | 1.11 | 0.46 | 2.68 | 0.73 | 1.17 | 0.73 | 1.88 | 0.80 | 1.61 | 0.77 | 3.36 |
| ICP | 0.13 | 3.84 | 1.06 | 13.94 | 0.16 | 2.77 | 0.89 | 8.60 | NC | NC | NC | NC | 0.19 | 1.36 | 0.17 | 10.58 | NC | NC | NC | NC |
| Polyhydramnios | 0.51 | 1.72 | 0.60 | 4.89 | 0.80 | 1.56 | 0.70 | 3.48 | 0.96 | 1.79 | 0.24 | 13.24 | 0.45 | 2.27 | 0.88 | 5.82 | NC | NC | NC | NC |
| Oligohydramnios | 0.91 | 1.19 | 0.68 | 2.10 | 1.55 | 0.75 | 0.46 | 1.22 | 0.97 | 1.17 | 0.42 | 3.25 | 1.13 | 1.01 | 0.55 | 1.83 | 1.59 | 0.48 | 0.12 | 1.96 |
| Chorioamnionitis | 0.53 | 1.64 | 0.74 | 3.63 | 0.97 | 1.19 | 0.61 | 2.32 | 0.71 | 1.76 | 0.42 | 7.38 | 1.80 | 0.75 | 0.23 | 2.40 | 0.28 | 2.93 | 1.04 | 8.26 |
CI confidence interval, cOR crude odds ratio, aOR djusted odds ratio. Mixed infertility refers to multiple infertility-related diagnosis; SP singleton pregnancies, GH gestational hypertension, PPE preterm preeclampsia, GDM gestational diabetes mellitus, pPROM preterm premature rupture of membranes, PH postpartum haemorrhage, ICP intrahepatic cholestasis of pregnancy
Bold indicates significant differences; NC not calculated due to low numbers
Note: Logistic regression analysis was adjusted for age, gravidity, parity, pre-pregnancy obesity, birth plurality, and history of previous caesarean section. The reference group of logistic regression is spontaneous control pregnancy