Fig. 1.

Exposure to diesel exhaust particles results in systemic and peri-bronchial inflammation. a Graphs representing total white blood cell count and b blood differential counts in 4–6 week-old male C57Bl/6 wildtype mice, on either control (LF) or high-fat (HF) diet exposed to either saline (control) or diesel exhaust particles (DEP – 35 μg PM) for 1 week. c Representative images of H&E staining of lung sections in control and exposed groups after 30 days of exposure. d Quantification of histological injury score in mice exposed to either DEP or saline. Images displayed are using 20X magnification. Scale bar = 240 μm. Data are depicted as mean ± SEM with *p < 0.05 compared to LF Control, †p < 0.05 compared to HF Control, ‡p < 0.05 compared to LF DEP by two way ANOVA