Fig. 2.

Exposure to DEP results in increased levels of immunoglobulins in the BALF. a Quantification of IgA (ng/ml) and b IgG (ng/ml), in the bronchoalveolar lavage fluid (BALF) of 4–6 week-old male C57Bl/6 wildtype mice, on either control (LF) or high-fat (HF) diet exposed to either saline (control) or diesel exhaust particles (DEP – 35 μg PM) twice a week for a total of 30 days, by ELISA. c Mean normalized gene expression of IgA receptor - pIgR and d IgG receptor – FcRn in lung tissues, as determined by RT-qPCR. Data are depicted as mean ± SEM with *p < 0.05 compared to LF Control, †p < 0.05 compared to HF Control, ‡p < 0.05 compared to LF DEP by two way ANOVA