Fig. 9.

Exposure to diesel exhaust particles results in the activation of TLR2 and TLR4. Mean normalized gene expression of (a) TLR2 and (b) TLR4 mRNA transcript expression within the lungs of C57Bl/6 wildtype mice, as quantified by RT-qPCR, on either control (LF) or high-fat (HF) diet, exposed to either saline (control) or diesel exhaust particles (DEP − 35 μg PM) twice a week for a total of 30 days. Data are depicted as mean ± SEM with *p < 0.05 compared to LF Control, †p < 0.05 compared to HF Control, ‡p < 0.05 compared to LF DEP by two way ANOVA