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. 2021 Jan 8;14:8. doi: 10.1186/s13048-020-00762-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — miR-145 was inversely correlated with ARL5B in EOC. a mRNA level of ARL5B in ovarian cancer tissue samples (n = 31) was higher than in normal ovarian tissue samples (n = 15). b Scatter diagram showing ARL5B expression and miR-145 expression by qRT-PCR and their correlations (R² = 0.219, P = 0.008) in 31 EOC tissue samples. c Immunohistochemistry results indicate a negative correlation between miR-145 and ARL5B in EOC epithelia. d Quantitative real-time PCR results show a negative correlation between ARL5B and miR-145 in both SKOV3 and 3AO cells. Scale bar, 50 µm