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. 2021 Jan 9;22:5. doi: 10.1186/s12865-020-00389-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Non-neutralizing ZIKV antibodies cause enhancement of ZIKV infection at higher concentration without virus neutralization. a Vero cells were infected with ZIKV RVPs in the presence of different dilutions of ZIKV antibodies and number of GFP positive cells analyzed 72 h post infection. Percent infection was determined as above. b K562 cells were infected with ZIKV RVPs in the presence different dilutions of ZIKV antibodies and number of GFP positive cells analyzed 48 h post infection. Percent ADE was determined as above. c Pooled average of data from all WNV seropositive donors was plotted for neutralization of ZIKV and WNV infection. d Pooled average of data from all WNV seropositive donors was plotted for enhancement of ZIKV and WNV infection