Table 3.
Crude and Adjusted HRs for 14-Day and 60-Day Mortality by DM-EHG Subgroup
| Crude mortality | 14-day mortality |
60-day mortality |
||||
|---|---|---|---|---|---|---|
| HR | P | CI | HR | P | CI | |
| No DM, No EHG | ref | … | … | ref | … | … |
| No DM, Yes EHG | 3.12 | .014 | 1.26-7.76 | 3.04 | .009 | 1.33-6.98 |
| Yes DM, No EHG | 1.36 | .603 | 0.43-4.26 | 1.58 | .315 | 0.65-3.89 |
| Yes DM, Yes EHG | 0.92 | .850 | 0.38-2.22 | 1.25 | .530 | 0.63-2.48 |
| Adjusted mortalitya | 14-day mortality |
60-day mortality |
||||
|---|---|---|---|---|---|---|
| HR | P | CI | HR | P | CI | |
| No DM, No EHG | ref | … | … | ref | … | … |
| No DM, Yes EHG | 7.51 | .008 | 1.70-33.24 | 6.97 | .004 | 1.86-26.13 |
| Yes DM, No EHG | 1.94 | .403 | 0.41-9.24 | 3.31 | .062 | 0.94-11.64 |
| Yes DM, Yes EHG | 1.16 | .852 | 0.25-5.42 | 2.62 | .127 | 0.76-9.00 |
Abbreviations: A1C = hemoglobin A1C; CI = confidence interval; DM = diabetes mellitus; EHG = early-onset hyperglycemia; HR = hazard ratio; ICU = intensive care unit.
a
Adjusted for age, sex, hypertension, pre-ICU hemoglobin A1C, glucocorticoid therapy within 48 hours after ICU admission, cardiovascular disease (presence of either congestive heart failure or coronary artery disease), chronic kidney disease, and end-stage renal disease on renal replacement therapy.