Table 1.

Estimates and 95% confidence intervals for the clinically relevant model parameters

Variable	Parameter value	95% CI lower	95% CI upper	p value
Age	−0.0087	−0.0149	−0.0025	0.003
Foveal contour	−0.1771	−0.3278	−0.0264	0.011
Retinal thickness	0.0011	0.0003	0.0020	0.003
Subretinal fibrosis	−0.0049	−0.0065	−0.0033	6.01 × 10–5
Subretinal fluid	−0.0013	−0.0022	−0.0004	0.003
Sub-RPE fibrosis	−0.0035	−0.0047	−0.0022	7.20 × 10–8
Sub-RPE fluid	−0.0001	−0.0005	0.0004	0.400
Choroidal thickness	0.0060	0.0036	0.0084	4.38 × 10–6
Atrophy level	−0.0034	−0.0045	−0.0022	9.32 × 10–9
ELM intact	1.2813	0.9799	1.5826	< 1.0 × 10–8
No. of cysts	−0.1264	−0.1726	−0.0802	4.15 × 10–8

Note: a concave retinal profile at the fovea was coded as −1, whilst a non-concave profile was coded as 0. An intact ELM was coded as 1, whilst the ELM not being intact was coded as 0

RPE retinal pigment epithelial, ELM external limiting membrane