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. 2020 Aug 4;56(1):257–266. doi: 10.1038/s41409-020-01014-x

Table 1.

Patient characteristics.

Patients (total) MSD + MD MMD p value
Total N 569 463 106
Age of patient at SCT Median (range) 10.2 (0.9–23.1) 10.3 (0.9–23.1) 8.9 (1.0–20.6) 0.130
  ≤4 years N 69 12% 52 11% 17 16% 0.315
  >4 and ≤12 years N 293 51% 238 51% 55 52%
  >12 years N 207 36% 173 37% 34 34%
Age of donor
  ≤18 years N 107 21% 105 25% 2 2% <0.001
  >18 and ≤35 years N 205 41% 182 43% 23 28%
  >35 years N 191 38% 135 32% 56 69%
  Patients with stem cell source CB N 26 9 17
  Missing N 40 32 8
Gender donor/patient
  Donor-female, patient-male N 141 25% 117 26% 24 24% 0.638
  Others N 413 75% 335 74% 78 76%
  Missing N 15 11 4
Remission status at SCT
  CR1 N 214 38% 178 38% 36 36% 0.022
  CR2 N 270 47% 225 49% 45 42%
  CR > 2 N 85 15% 60 13% 25 24%
Phenotype of patient
  b-cell N 407 74% 330 73% 77 77% 0.243
  t-cell N 127 23% 106 23% 21 21%
  Other N 18 3% 16 4% 2 2%
  Not available N 17 11 6
Graft source/manipulation
  BM unmanipulated N 330 60% 310 69% 20 20% <0.001
  PB unmanipulated N 135 24% 118 26% 17 17%
  CB unmanipulated N 26 5% 9 2% 17 17%
  Ex vivo manip. PB N 62 11% 15 3% 47 47%
  Graft manipulation data missing N 16 11 5
CMV status donor/patient
  Donor-negative, patient-positive N 113 21% 93 21% 20 20% 0.463
  Others N 431 79% 352 79% 79 80%
  Missing 25 18 7
TBI
  No N 104 19% 70 15% 34 34% <0.001
  Yes N 448 81% 382 85% 66 66%
  Missing N 17 11 6