Table 2.
Ultrasound elastography of the liver and native T1 times and extracellular volume fractions of the liver and spleen
| Fontan | Control n=15 | P-valuea Fontan vs. control | Single left ventricle n=24 | Single right ventricle n=19 | P-valuea single left vs. single right ventricle | |
|---|---|---|---|---|---|---|
| Shear-wave elastography | ||||||
| Liver median, in m/s, n=45b | 1.91±0.14 | 1.23±0.10 | <0.001 | 1.93±0.14 | 1.94±0.12 | 0.7 |
| MR, T2*, T1 mapping/extracellular volume fraction | ||||||
| Liver T1, in ms, n=35b | 774±44 | 632±52 | <0.001 | 756±49 | 787±31 | 0.03 |
| Liver extracellular volume fraction, in %, n=35b | 47.4±5.0 | 34.6±3.8 | <0.001 | 46.4±4.8 | 48.0±5.4 | 0.4 |
| Spleen T1, in ms, n=35b | 1,169±62 | 1,139±89 | 0.2 | 1,159±52 | 1,176±72 | 0.4 |
| Spleen extracellular volume fraction, in %, n=35b | 30.7±3.1 | 30.5±1.9 | 0.7 | 30.8±3.1 | 30.6±3.1 | 0.8 |
| Liver T2*, in ms, n=32b | 32.0±3.6 | 30.0±3.2 | 0.05 | 32.1±4.0 | 32.0±4.1 | 0.8 |
| Spleen T2*, in ms, n=31b | 60±19 | 49±10 | 0.04 | 62±22 | 60±15 | 0.7 |
| Spleen length, in cmb | 12±2 (8–19) | |||||
aP-value <0.05 is significant (bold)
bValues are the mean ± standard deviation (range)