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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Sci Total Environ. 2020 Nov 14;758:143707. doi: 10.1016/j.scitotenv.2020.143707

Figure 2: Dust Extract Adipogenic Activity is Correlated with Thyroid Receptor Beta Antagonism.

Figure 2:

Interrogation of thyroid receptor beta (TRβ) antagonism as putative molecular mechanism that may contribute to normalized triglyceride per cell. (A) Spearman’s correlation comparing normalized triglyceride accumulation per cell relative to maximal intra-assay response for rosiglitazone (normalized to DNA content) versus TRβ antagonism as measured via reporter gene assay in human embryonic kidney cells. (B) Spearman’s correlation comparing pre-adipocyte proliferation relative to a differentiated vehicle control versus TRβ antagonism. Significant correlations were determined using p < 0.05 using GraphPad Prism 8.0.