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. Author manuscript; available in PMC: 2022 Jan 15.
Published in final edited form as: Acta Biomater. 2020 Oct 29;120:224–239. doi: 10.1016/j.actbio.2020.10.011

Fig 3. Time course of spatial mobilization and puncta formation of STIM1 with ER Ca2+ depletion.

Fig 3.

(A) Dental pulp stem cells transfected with CFP-STIM1 were stimulated by 500 ng/ml DMP1 for various time periods to trigger ER Ca2+ release. Oligomerization and mobilization of STIM1 were monitored by live-cell imaging using confocal microscopy. Note “puncta” formation with ER store depletion.

(B) Changes in cell morphology of DPSC–GFP-STIM1 overexpressing cells with ER Ca2+ release triggered by the addition of DMP1. Note formation of extensive cellular process.