Table 1.
Number of differentially expressed transcripts after stress exposure on each strain. Numbers of mRNAs regulated in the five stress conditions in three genetic backgrounds: wild type, eIF2α-S52A and sty1Δ cells. mRNA up/down, and translation up/down indicate numbers of mRNAs whose expression is significantly up- or down-regulated at the transcriptome or translational levels, respectively (see Methods for details). Annotated lists containing these genes are presented in Supplementary Dataset S3
mRNA up | mRNA down | Translation up | Translation down | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
wt | S52A | sty1Δ | wt | S52A | sty1Δ | wt | S52A | sty1Δ | wt | S52A | sty1Δ | |
CdSO4 | 443 | 410 | 176 | 302 | 269 | 111 | 57 | 37 | 17 | 320 | 212 | 103 |
HS | 621 | 468 | 306 | 404 | 364 | 149 | 39 | 18 | 1 | 229 | 124 | 5 |
H2O2 | 186 | 120 | 25 | 36 | 50 | 18 | 7 | 1 | 3 | 49 | 0 | 65 |
MMS | 142 | 147 | 0 | 8 | 22 | 0 | 4 | 2 | 0 | 1 | 0 | 0 |
Sorbitol | 193 | 198 | 0 | 113 | 109 | 0 | 0 | 0 | 0 | 1 | 1 | 7 |