Figure 6.

PIM1-mediated maintenance of telomere length is TERT dependent. (A) Western-blot image of TERT expression in NTg, PIM1, and Pim1-KO cardiomyocytes. (B) Quantification of TERT protein expression in cardiomyocytes. n = 5 biological×1–3 technical replicates per group, error bars represent SEM, **P < 0.01 and ***P < 0.001 as measured by one-way ANOVA followed by Tukey’s multiple comparison test. (C) qRT–PCR quantification of telomere lengths in transduced cardiomyocytes. n = 3–7 per group, error bars represent SEM, **P < 0.01 as measured by one-way ANOVA followed by Tukey’s multiple comparison test.