2. Univariate and multivariate analysis of OS in training cohort (N=687).
| Variables | No. | Univariate analysis | Multivariate analysis | ||
| P | HR (95% CI) | P | |||
| OS, overall survival; NOS, not otherwise specified; LNR, lymph node rate; LODDS, log odds of positive lymph nodes; HR, hazard ratio; 95% CI, 95% confidence interval. | |||||
| Sex | |||||
| Female | 323 | Reference | − | − | |
| Male | 364 | 0.928 | − | − | |
| Age (year) | |||||
| <45 | 88 | Reference | Reference | ||
| 45−59 | 232 | 0.845 | 1.248 (0.884−1.763) | 0.208 | |
| ≥60 | 367 | 0.123 | 1.895 (1.352−2.657) | <0.001 | |
| Race | |||||
| Other | 159 | Reference | Reference | ||
| Black | 81 | 0.028 | 1.452 (1.016−2.074) | 0.041 | |
| White | 447 | 0.190 | 1.114 (0.862−1.440) | 0.409 | |
| Grade | |||||
| I | 1 | Reference | − | − | |
| II | 21 | 0.989 | − | − | |
| III | 638 | 0.990 | − | − | |
| IV | 27 | 0.989 | − | − | |
| Size (cm) | |||||
| <3.5 | 247 | Reference | Reference | ||
| 3.5−6.8 | 260 | <0.001 | 1.128 (0.847−1.502) | 0.408 | |
| >6.8 | 180 | <0.001 | 1.705 (1.245−2.334) | <0.001 | |
| Stage | |||||
| I | 149 | Reference | − | − | |
| II | 155 | <0.001 | − | − | |
| III | 307 | <0.001 | − | − | |
| IV | 76 | <0.001 | − | − | |
| T stage | |||||
| T1 | 129 | Reference | Reference | ||
| T2 | 80 | 0.030 | 1.395 (0.784−2.481) | 0.257 | |
| T3 | 226 | <0.001 | 2.743 (1.711−4.396) | <0.001 | |
| T4a | 212 | <0.001 | 4.225 (2.632−6.783) | <0.001 | |
| T4b | 40 | <0.001 | 5.066 (2.823−9.092) | <0.001 | |
| N stage | |||||
| N0 | 216 | Reference | − | − | |
| N1 | 112 | <0.001 | − | − | |
| N2 | 115 | <0.001 | − | − | |
| N3a | 159 | <0.001 | − | − | |
| N3b | 85 | <0.001 | − | − | |
| M stage | |||||
| M0 | 611 | Reference | Reference | ||
| M1 | 76 | <0.001 | 2.041 (1.521−2.740) | <0.001 | |
| Site | |||||
| C16.0-Cardia, NOS | 90 | Reference | Reference | ||
| C16.1-Fundus of stomach | 17 | 0.083 | 0.578 (0.243−1.377) | 0.216 | |
| C16.2-Body of stomach | 84 | 0.616 | 0.988 (0.647−1.508) | 0.955 | |
| Gastric antrum (including pylorus) | 219 | 0.688 | 1.000 (0.707−1.413) | 0.998 | |
| C16.5-lesser curvature of stomach, NOS | 105 | 0.731 | 0.968 (0.649−1.446) | 0.875 | |
| C16.6-greater curvature of stomach, NOS | 43 | 0.430 | 0.896 (0.528−1.520) | 0.683 | |
| Stomach, NOS | 129 | 0.002 | 1.186 (0.819−1.719) | 0.366 | |
| LNR | |||||
| LNR1 | 295 | Reference | − | − | |
| LNR2 | 224 | <0.001 | − | − | |
| LNR3 | 168 | <0.001 | |||
| LODDS | |||||
| LODDS1 | 223 | Reference | Reference | <0.001 | |
| LODDS2 | 163 | <0.001 | 1.963 (1.410−2.732) | <0.001 | |
| LODDS3 | 191 | <0.001 | 2.186 (1.582−3.020) | <0.001 | |
| LODDS4 | 110 | <0.001 | 3.194 (2.240−4.554) | <0.001 | |