3. Univariate and multivariate analysis of CSS in training cohort (N=687).
| Variables | No. | Univariate analysis | Multivariate analysis | ||
| P | HR (95% CI) | P | |||
| CSS, cancer-specific survival; NOS, not otherwise specified; LNR, lymph node rate; LODDS, log odds of positive lymph nodes; HR, hazard ratio; 95% CI, 95% confidence interval. | |||||
| Sex | |||||
| Female | 323 | Reference | − | − | |
| Male | 364 | 0.675 | − | − | |
| Age (year) | |||||
| <45 | 88 | Reference | Reference | ||
| 45−59 | 232 | 0.926 | 1.174 (0.825−1.670) | 0.373 | |
| ≥60 | 367 | 0.329 | 1.709 (1.210−2.414) | 0.002 | |
| Race | |||||
| Other | 159 | Reference | Reference | ||
| Black | 81 | 0.068 | 1.372 (0.942−1.996) | 0.099 | |
| White | 447 | 0.250 | 1.101 (0.844−1.438) | 0.478 | |
| Grade | |||||
| I | 1 | Reference | − | − | |
| II | 21 | 0.990 | − | − | |
| III | 638 | 0.990 | − | − | |
| IV | 27 | 0.990 | − | − | |
| Size (cm) | |||||
| <3.5 | 247 | Reference | Reference | ||
| 3.5−6.8 | 260 | <0.001 | 1.155 (0.854−1.564) | 0.350 | |
| >6.8 | 180 | <0.001 | 1.730 (1.248−2.416) | 0.001 | |
| Stage | |||||
| I | 149 | Reference | − | − | |
| II | 155 | <0.001 | − | − | |
| III | 307 | <0.001 | − | − | |
| IV | 76 | <0.001 | − | − | |
| T stage | |||||
| T1 | 129 | Reference | Reference | ||
| T2 | 80 | 0.016 | 1.568 (0.843−2.918) | 0.156 | |
| T3 | 226 | <0.001 | 3.011 (1.794−5.054) | <0.001 | |
| T4a | 212 | <0.001 | 4.609 (2.743−7.744) | <0.001 | |
| T4b | 40 | <0.001 | 5.364 (2.861−10.057) | <0.001 | |
| N stage | |||||
| N0 | 216 | Reference | − | − | |
| N1 | 112 | <0.001 | − | − | |
| N2 | 115 | <0.001 | − | − | |
| N3a | 159 | <0.001 | − | − | |
| N3b | 85 | <0.001 | − | − | |
| M stage | |||||
| M0 | 611 | Reference | Reference | ||
| M1 | 76 | <0.001 | 2.050 (1.514−2.775) | <0.001 | |
| Site | |||||
| C16.0-Cardia, NOS | 90 | Reference | Reference | ||
| C16.1-Fundus of stomach | 17 | 0.012 | 0.637 (0.267−1.521) | 0.310 | |
| C16.2-Body of stomach | 84 | 0.581 | 0.978 (0.632−1.515) | 0.921 | |
| Gastric antrum (including pylorus) | 219 | 0.886 | 0.950 (0.663−1.362) | 0.781 | |
| C16.5-lesser curvature of stomach, NOS | 105 | 0.475 | 0.877 (0.576−1.336) | 0.541 | |
| C16.6-greater curvature of stomach, NOS | 43 | 0.392 | 0.870 (0.501−1.512) | 0.622 | |
| Stomach, NOS | 129 | 0.002 | 1.163 (0.793−1.705) | 0.440 | |
| LNR | |||||
| LNR1 | 295 | Reference | − | − | |
| LNR2 | 224 | <0.001 | − | − | |
| LNR3 | 168 | <0.001 | |||
| LODDS | |||||
| LODDS1 | 223 | Reference | Reference | <0.001 | |
| LODDS2 | 163 | <0.001 | 1.999 (1.407−2.839) | <0.001 | |
| LODDS3 | 191 | <0.001 | 2.274 (1.617−3.199) | <0.001 | |
| LODDS4 | 110 | <0.001 | 3.292 (2.265−4.785) | <0.001 | |