S5.
Performance of oral microbiome-based model for prediction risk of malignant esophageal lesions stratified by case type in Anyang, China, 2006−2017. (A) ROC based on 52 screen-endoscopic-detected SDA cases (providing 84 oral specimens) and 104 matched controls (providing 162 oral specimens) [AUC: 0.90 (95% CI, 0.86−0.95)]; (B) ROC based on 32 clinically diagnosed SDA cases (providing 59 oral specimens) and 64 matched controls (providing 123 oral specimens) [AUC: 0.88 (95% CI, 0.81−0.94)]. ROC, receiver operating characteristic; SDA, severe dysplasia and above; AUC, area under the receiver operating characteristic curve; 95% CI, 95% confidence interval; ESCC, esophageal squamous cell carcinoma.