Table 3.

Comparisons of female patients corrected for TOF without and with history of VA, and markers for VA adjusted for age

	TOF without VA n=63 (79%)	TOF with VA n=17 (21%)	P value	OR (95% CI)	P value
Age, years	36±9	40±9	0.08
Height, cm	165±7	166±9	0.81
Weight, kg	68±13	63±10	0.25
History of pregnancy, n (%)	39 (61)	16 (94)	0.02	13 (1.5 to 113.2)	0.02*
HR, bpm	68±11	62±8	0.13
SBP, mm Hg	115±11	115±13	0.98
DBP, mm Hg	68±9	71±12	0.44
QTc duration, ms	458±31	450±27	0.52
Exercise capacity, W	125±25	140±26	0.13
NYHA class	1 (1–3)	1 (1–2)	0.66
NT-proBNP, ng/L	139 (30–465)	211 (127–836)	0.007	1.4 (1.1 to 1.7)	0.017*
QRS duration, ms	135 (82–174)	133 (86–152)	0.45
RV EDV, mL	21.1±4.1	22.7±3.6	0.16
RV ESV, mL	11.1±2.6	11.8±2.5	0.33
RV FAC, %	47±7	47±8	0.93
RV D3, cm	7.3±0.7	7.4±0.7	0.54
PV vel, m/s	1.9±0.6	1.8±0.4	0.39
Mod-sev PV reg	12 (19%)	2 (12%)	0.47
LV MD, ms	43±13	48±16	0.24
LV GLS, %	−19.2±3.1	−17.5±3.6	0.10
RV MD, ms	39±14	50±8	0.009 0.016	2.1 (1.3 to 7.5) 5.7 (3.5 to 9.2)	0.01* 0.03†
RV GLS, %	−19.7±4.1	−18.3±4.1	0.28
RVOT, cm	2.9±0.4	3.1±0.6	0.31
LVEF, %	56±9	54±8	0.39

Data are presented as mean±SD or median with range, as appropriate; p value from Student’s t-test or Mann-Whitney U test as appropriate, and multivariable logistic regression.

*Adjusted for age at VA.

†Adjusted for age at echocardiography.

DBP, diastolic blood pressure; EDV, end-diastolic volume; ESS, end-systolic strain; ESV, end-systolic volume; GLS, global longitudinal strain; HR, heart rate; LV, left ventricular; LVEF, left ventricular ejection fraction; MD, mechanical dispersion; NT-proBNP, N-terminal pro-brain natriuretic peptide; NYHA, New York Heart Association classification; PV, pulmonary valve; RV, right ventricular; RV D3, right ventricular longitudinal diameter; RV FAC, right ventricular fractional area change; RVOT, right ventricular outflow tract; SBP, systolic blood pressure; TOF, tetralogy of Fallot; VA, ventricular arrhythmia.