Table 5.

HR with 95% CI of developing RA among drinkers with different combinations of weekly alcohol consumption and smoking

Alcohol consumption	Ever smoking	N	Person years	Incident RA	HR (95% CI)*	HR (95% CI)†	AP (95% CI)
Moderate-high	No	9001	164 529	87 (1.0)	1.0 (reference)	1.0 (reference)
Low	No	11 195	198 686	133 (1.2)	1.14 (0.87–1.50)	1.10 (0.84–1.45)
Moderate-high	Yes	8831	158 256	125 (1.4)	1.37 (1.04–1.80)	1.32 (1.00–1.74)
Low	Yes	6566	113 202	129 (2.0)	1.94 (1.48–2.55)	1.81 (1.37–2.38)	0.22 (0.02–0.52)

Significant HRs are in bold.

*Adjusted for gender.

†Adjusted for gender, educational status, body mass index, physical activity and cardiovascular disease.

AP, attributable proportion due to interaction; RA, rheumatoid arthritis.