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. 2021 Jan 6;16:47–60. doi: 10.2147/IJN.S282154

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© 2021 Wei et al.

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Anti-tumor activity in xenograft models in vivo. (A) H&E, (B) TUNEL and (D) Ki-67 staining on tumor sections collected from Hepa1-6 tumor-bearing mice after various treatments, (C and E) represent the expression of TUNEL-positive cells and Ki67-positive cells, respectively. Data are expressed as the mean ± SD, n=4 for each group. **P < 0.01, EMS group and RADA16-I-EM group vs Control group, RADA16-I-EM group vs EMS group. The red arrows “↗” in figures (B and D) represent tumor cell apoptosis and proliferation, respectively.