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. 2021 Jan 6;14:83–95. doi: 10.2147/OTT.S277831

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© 2021 Li et al.

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Circ_0006404 silencing suppresses the PCa tumor growth in vivo. (A) The length and width of tumors were measured using vernier caliper every 7 d, and the tumor volume was calculated by (width² × length)/2. (B) Mice in sh-NC group and sh-circ_0006404 group were dissected at 28 d after injection, and the weight of tumors was detected using analytical balance. (C and D) qRT-PCR was conducted to detect the abundance of circ_0006404 and miR-1299 in resected tumor tissues. (E) The protein expression of CFL2 was measured in resected tumor tissues in sh-NC group and sh-circ_0006404 group by Western blot assay. *P<0.05.