Table 4.
Levels of IL-6, IL-10, IL-1β, TNF-α and IFN-γ in Serum and Liver Tissue of Mice (N=10/Group)
| Groups | IL-6 | IL-10 | IL-1β | TNF-α | IFN-γ | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Serum (pg/mL) |
Liver (pg/mgprot) |
Serum (pg/mL) |
Liver (pg/mgprot) |
Serum (pg/mL) | Liver (pg/mgprot) |
Serum (pg/mL) |
Liver (pg/mL) |
Serum (pg/mL) |
Liver (pg/mL) |
|
| Normal | 5.68±0.71bA | 4.98±0.47b | 58.00±3.83c | 176.85±17.49a | 21.19±3.35b | 12.92±1.34c | 61.57±7.32c | 84.29±17.37d | 86.17±6.76c | 80.48±8.37d |
| Model | 8.69±1.34a | 6.39±0.54a | 45.11±4.76d | 124.19±11.96d | 26.21±5.08a | 16.20±1.62a | 97.85±10.38a | 119.32±19.4a | 110.70±15.41a | 112.76±12.34a |
| Low | 5.71±0.49b | 4.81±0.37bc | 60.68±4.38b | 137.81±15.94c | 19.30±1.84c | 15.02±1.05b | 82.98±5.71b | 107.11±18.13b | 90.64±7.37b | 100.25±16.22b |
| High | 4.16±1.29c | 4.42±0.65c | 78.06±7.22a | 146.85±19.84b | 13.94±2.07d | 12.45±2.47cd | 54.49±6.95c | 97.87±11.18c | 65.38±6.38c | 85.31±13.85c |
Notes: Model: treated with D-Gal/LPS (250 mg/kg·bw and 25 mg/kg·bw, last day) injection; Low: mice treated with D-Gal/LPS (250 mg/kg·bw and 25 mg/kg·bw, last day) injection after Lactobacillus plantarum KSFY06 (2.5×109 CFU/kg·bw, per day) oral administration; High: treated with D-Gal/LPS (250 mg/kg·bw and 25 mg/kg·bw, last day) injection after Lactobacillus plantarum KSFY06 (2.5×1010 CFU/kg·bw, per day) oral administration. a–dThere was significant difference in different letters in the same column (P < 0.05), which was determined by Duncan’s multiple range test. AValues presented are the mean±standard deviation (SD).