Figure 1.

Schematic representation of ECM hydrogel from preparation to application. The native tissues can achieve a diversity of ECM hydrogels via combination of physical, chemical and biological approaches together. The prepared ECM hydrogels themselves with/without incorporating growth factors and/or stem cells are used for tissue repair and regeneration, including spinal cord injury, peripheral nerve injury and myocardial infarction. Some of these may become a primary option for remodeling a variety of clinical tissues defects.