Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 24;47(2):732–740. doi: 10.3892/ijmm.2020.4833

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Tube formation of retinal microvascular endothelial cells is inhibited by the blocking of NLRP3. (A) The tube formation was markedly enhanced in the HG group of HRMECs and was inhibited by blocking of NLRP3. Then, the (B) tube meshes, (C) nodes and (D) tube length were counted, and the results revealed that the HRMECs in the HG group formed more meshes and nodes than the control; the tube total length in the HG group was higher than that in the control group. However, after the blocking of NLRP3, the tube meshes, nodes and tube length were reduced compared with the HG group. ^*P<0.05 and ^**P<0.01 compared with the control; ^#P<0.05 and ^##P<0.01 compared with the relative HG-induced HRMEC cell group. NLRP3, NLR family pyrin domain containing 3; HG, high glucose; HRMECs, human retinal microvascular endothelial cells.