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. 2020 Dec 16;47(2):633–642. doi: 10.3892/ijmm.2020.4820

Figure 3.

Figure 3

Rev-erbα expression in Raw264.7 cells is augmented by melatonin. Rev-erbα (A) mRNA and (B) protein expression in Raw264.7 cells cultured for 7 days with RANKL (100 ng/ml) and M-CSF (30 ng/ml) in the presence of varying concentrations (0.1 or 1 µmol) of melatonin for 48 h. Data are represented as the mean ± SD (n=3). **P<0.01. RANKL, receptor activator of nuclear factor-κB ligand; M-CSF, macrophage colony-stimulating factor; Rev-erbα/NR1D1, nuclear receptor subfamily 1 group D member 1.