Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential mechanism by which melatonin may affect RANKL-induced osteoclastogenesis. Melatonin may first decrease miR-882 expression, then augment Rev-erbα expression and decrease cathepsin K expression, ultimately inhibiting osteoclastogenesis. RANKL, receptor activator of nuclear factor-κB ligand; miR, microRNA; Rev-erbα/NR1D1, nuclear receptor subfamily 1 group D member 1.
