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. 2020 Dec 14;47(2):523–532. doi: 10.3892/ijmm.2020.4816

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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FGD5-AS1 knockdown decreases DDP resistance in DDP-resistant LAD cells. (A) Reverse transcription-quantitative PCR showed the relative FGD5-AS1 expression in A549/DDP and HCC827/DDP cells transfected with sh-NC and sh-FGD5-AS1. (B) Cell viability was determined by a Cell Counting Kit-8 assay in DDP-resistant LAD cells treated with 4 µg/ml DDP. (C) Cell invasion and (D) migration were evaluated by a Transwell assay (magnification, ×200). The data are presented as the mean ± SD. ^*P<0.05. FGD5-AS1, FGD5-antisense 1; DDP, cisplatin; LAD, lung adenocarcinoma; sh-, short hairpin RNA; NC, negative control.