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. 2020 Dec 14;47(2):523–532. doi: 10.3892/ijmm.2020.4816

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Copyright: © Zhu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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FGD5-AS1 enhances DDP resistance via miR-142 in DDP-resistant lung adenocarcinoma cells. (A) Reverse transcription-quantitative PCR showed the expression of FGD5-AS1 in A549 cells transfected with FGD5-AS1 overexpression plasmid. (B) A Cell Counting Kit-8 assay showed the viability of A549/DDP cells transfected with NC mimics, miR-142 mimics, miR-142 mimics + pcDNA3.1 and miR-142 mimics + FGD5-AS1. Transwell assays showed the (C) invasion and (D) migration of A549/DDP cells treated with DDP in different groups (magnification, ×200). The data are presented as the mean ± SD. ^*P<0.05. FGD5-AS1, FGD5-antisense 1; DDP, cisplatin; NC, negative control; miR, microRNA.