Fig. 19.
Potential mechanisms of SARS-COV-2-induced injury of multiple organs and pharmacological effects of CLQ-OH on COVID-19. Blue arrows indicate the actions of SARS-COV-2. ACE2 is key for SARS-COV-2 entering cells in human organs. Red dashed lines indicate the potential mechanisms of the therapeutic and toxic effects of CLQ-OH on SARS-COV-2 and organs in COVID-19 patients. Image reproduced from Ref. [87] with permission from Elsevier