Table 4.

Association of CYP4F2, APOE and CYP2A6 SNPs with variability on warfarin required doses

Gene	SNP ID	Genotype	Initiation dose	Overall P-value*	Maintenance dose	Overall P-value*
		CC	35.87 [15.45]		36.66 [17.11]
CYP4F2	rs2108622	CT	38.22 [14.67]	0.21	40.24 [19.99]	0.54
		TT	44.59 [49.83]		39.43 [12.76]
		CC	36.79 [14.33]		38.24 [17.24]
APOE	rs74125	TC	53.39 [62.10]	0.02	38.60 [25.09]	0.48
		TT	38.40 […….]
		GG	38.13 [37.72]		35.49 [17.74]
APOE	rs405509	GT	38.28 [15.55]	0.98	41.01 [18.36]	0.30
		TT	37.60 [14.39]		37.98 [17.04]
CYP2A6	rs1801272	AA	38.16 [22.83]	0.67	38.56 [16.79]	0.99
		TA	33.64 [34.87]		38.60 [45.86]

*One-way ANOVA test with P-value < 0.05 is considered significant, Mean Standard deviation in square brackets.