. 2021 Jan 1;18(3):811–820. doi: 10.7150/ijms.51484

Table 1.

The summary of included studies for meta-analysis

Study	Country	Sample size	Formation of resistant starch type 2 (RS2) and placebo	Dosage	Duration of treatment
Sirich 2014 ¹⁹	United States	20 patients and 20 controls	RS2: 15 g of high-amylose corn starch (Hi-maize 260), composed of approximately 40% digestible starch and 60% RS2;	1 sachet daily for 1 one week and 2 sachets daily for next weeks	6 weeks
Sirich 2014 ¹⁹	United States	20 patients and 20 controls	Placebo: 15 g of waxy corn starch.		6 weeks
Esgalhado 2018 ²²	Brazil	15 patient and 16 controls	RS2: 16 g due to starch gelatinization for cookies;	1 sachet daily	4 weeks
Esgalhado 2018 ²²	Brazil	15 patient and 16 controls	Placebo: 20 g manioc flour daily.	1 sachet daily	4 weeks
Khosroshahi 2018 ²⁰	Iran	22 patients and 22 controls	RS2: 20 g or 25 g of 60% RS2 in HAM-RS2 enriched crackers;	1 sachet daily	8 weeks
Khosroshahi 2018 ²⁰	Iran	22 patients and 22 controls	Placebo: regular wheat flour.	1 sachet daily	8 weeks
Khosroshahi 2019 ²¹	Iran	23 patients and 21 controls	RS2: 20 g or 25 g of 60% RS2 in HAM-RS2;	1 sachet daily	8 weeks
Khosroshahi 2019 ²¹	Iran	23 patients and 21 controls	Placebo: 20 g or 25 g of waxy corn starch.	1 sachet daily	8 weeks
Laffin 2019 ²³	Iran	9 patients and 11 controls	RS2: 20 g or 25 g of 60% RS2 in HAM-RS2 enriched crackers;	1 sachet daily	2 months
Laffin 2019 ²³	Iran	9 patients and 11 controls	Placebo: regular wheat flour.	1 sachet daily	2 months