Table 2.
Univariate and Multivariate Cox Proportional Hazards Model Analysis of Prognostic Factors for Overall Survival in Patients With PC.
| Parameters | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age (< 60 vs. ≥ 60) | 0.714 (0.452-1.302) | 0.820 | NA | NA |
| Gender (male vs. female) | 0.821 (0.589-1.577) | 0.501 | NA | NA |
| Pathological subtype (PDAC vs. mucinous carcinoma/acinar cell carcinoma) | 1.306 (0.811-2.960) | 0.175 | NA | NA |
| Tumor diameter (< 4 vs. ≥ 4) | 1.122 (0.759-2.518) | 0.464 | NA | NA |
| Tumor location (head vs. body and tail) | 1.297 (0.773-2.848) | 0.362 | NA | NA |
| Tumor differentiation (Well/moderately vs. poorly) | 1.744 (0.922-3.158) | 0.079 | NA | NA |
| CA19-9 level (< 37 vs. ≥ 37) | 0.869 (0.470-1.721) | 0.627 | NA | NA |
| Venous invasion (no vs. yes) | 1.930 (0.953-3.862) | 0.061 | NA | NA |
| Lymphatic metastasis (no vs. yes) | 2.728 (1.509-5.516) | 0.034* | 1.945 (0.970-3.480) | 0.073 |
| Clinical stage (I/II vs. III) | 2.184 (0.997-3.905) | 0.057 | NA | NA |
| Circ_001569 level (low vs. high) | 2.952 (1.821-7.778) | 0.028* | 2.256 (1.132-4.836) | 0.042* |
HR: hazard ratio, CI: confidence interval. *P < 0.05.