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. 2021 Jan 1;12(4):1231–1239. doi: 10.7150/jca.46971

Figure 2.

Figure 2

MiR-1262 inhibits cell proliferation, migration and invasion capability of MGC80-3, HGC-27 and OE33 adenocarcinoma cells. (A) miR-1262 inhibits cell growth of MGC80-3, HGC-27 and OE33 adenocarcinoma cells. Cell number was counted at 24 h, 48 h and 72 h after transfection. (B) Colony formation assays indicate that miR-1262 significantly suppresses colony formation of MGC80-3, HGC-27 and OE33 adenocarcinoma cells. (C) miR-1262 inhibits wound-healing in MGC80-3, HGC-27 and OE33 cells. Wound fields were observed directly after removal of inserts (0h) and cell migration was followed for 10 h or 20 h (MGC80-3 and HGC-27) and 20 h or 40 h (OE33). (D) miR-1262 suppresses invasion ability of MGC80-3, HGC-27 and OE33 cells. Cells on the lower surface of the chamber were stained by crystal violet at 48 h after transfection. Cell counts data of MGC80-3, HGC-27 and OE33 cells were presented as histogram. All results of the mean of triplicate assays with standard deviation of the mean are presented. *P< 0.05, **P< 0.01.