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JMJD8 interacts with EGFR and regulates its expression. (A) EGFR level changes with that of JMJD8; depletion of JMJD8 significantly reduced EGFR and p-EGFR levels. (B) Endogenous immunoprecipitation results showing that JMJD8 bound to EGFR in A549 and H1299 cells. (C) mRNA analysis of EGFR after JMJD8 knockdown or overexpression in A549 cells and H1299 cells.
