. 2021 Jan 1;12(4):1094–1104. doi: 10.7150/jca.51107

Table 2.

Clinical trials of immunotherapy in HGG

Author	Target	Number of patients	Vaccine	Result	Reference
Cloughesy et al²⁰¹⁹	PD1	16	neoadjuvant pembrolizumab	PFS:99.5d	101
	PD1	16	adjuvant nivolumab	PFS:72.5d
Desjardins et al²⁰¹⁸	CD155	61	PVSRIPO	OS:12.5mo	102
	--	104	--	OS:11.3mo
Brown et al²⁰¹⁶	IL13Rα2	1	IL13BBζ-CART	cytokines and immune cells in the cerebrospinal fluid increase	103
O'Rourke et al²⁰¹⁷	EGFR	10	CART-EGFRvIII	OS:251d	104
Hilf et al²⁰¹⁹	CD4/CD8	16	APVAC1/APVAC2	OS:29mo PFS:14.2mo	105