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Cell physiological function of CELSR3 in PCa. (A) CELSR3 mRNA expression in the CCLE dataset. (B) CELSR3 mRNA expression in PCa cell lines. (C) CELSR3 knockout efficacy. The expression of CELSR3 in siRNA target cells was remarkably decreased. (D) The proliferation ability in siRNA target cells was significantly suppressed compared to control cells. (E) The cell migration capacity in siRNA target cells was significantly suppressed compared to control cells. ***P<0.001; **** P<0.0001
