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. 2021 Jan 1;12(4):1115–1124. doi: 10.7150/jca.49567

Table 3.

Prognostic value of CELSR3 mRNA expression level for the disease-free survival (DFS) and overall survival (OS) via Cox proportional hazards model.

DFS OS
Hazard ratio (95% CI) P Hazard ratio (95% CI) P
Univariate analysis
CELSR3 mRNA 1.292(1.077-1.550) 0.006 1.785(1.341-2.376) <0.001
Gleason score 2.190(1.763-2.721) <0.001 2.973(1.342-6.585) 0.007
PSA 1.048(1.017-1.080) 0.002 1.062(1.004-1.124) 0.036
Pathological stage 2.615(1.733-3.945) <0.001 2.245(0.600-8.403) 0.230
Age 1.027(0.995-1.060) 0.095 1.053(0.956-1.161) 0.294
Multivariate analysis
CELSR3 mRNA 1.143(0.571-2.288) 0.614 4.591(1.584-13.309) 0.835
Gleason score 1.944(1.533-2.465) <0.001 2.361(1.104-5.049) 0.027
PSA 1.043(0.980-1.110) 0.155 1.005(1.001-1.009) 0.212
Pathological stage 1.702(1.043-2.778) 0.033 2.198(1.281-3.770) 0.987
Age 1.053(0.938-1.181) 0.705 1.024(0.974-1.077) 0.438