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. 2021 Jan 1;11(5):2247–2262. doi: 10.7150/thno.51666

Figure 3.

Figure 3

Blockade of NMDAR by Mem prevents hepatic steatosis in mice fed with HFD. (A-B) H&E stained histological images of liver sections from mice fed with HFD or normal chow diet for 12 weeks (Scale bars = 50 μm, n = 8). (C) Oil Red O staining of livers from mice fed with HFD or normal chow diet for 12 weeks (Scale bars = 50 μm). (D-F) Serum levels of ALT (D), AST (E), and ALP (F) of mice fed with HFD or normal chow diet for 12 weeks (n = 9). (G-I) Expression of Collagen I and Collagen III in the livers from mice fed with HFD or normal chow diet for 12 weeks by Western blotting (n = 5). (J-L) Expression of Tnf-α, Il-6, and Mcp-1 mRNA in livers from mice fed with HFD or normal chow diet for 12 weeks by RT-PCR (n = 6). (M-N) TNF-α and IL-6 in the livers from mice fed with HFD or normal chow diet for 12 weeks by ELISA (n = 6). *P < 0.05; **P <0.01; ***P <0.001. All data are presented as the mean ± SEM.